These guides set out what the published trials and meta-analyses found in men with confirmed
low testosterone, with the numbers and the confidence intervals rather than a summary
adjective. They include the results that do not favour treatment.
Start from where you are
Each step names the pages and guides for it, and the step after it.
Understanding symptoms.How assessment works covers what the symptoms are and are not, and what else explains them.
Next: what a diagnosis involves.
Assessment and diagnosis. The Diagnosis guides below set out what each guideline and Canadian label requires and where they differ.
Next: compare the ways to get care.
Treatment and monitoring.Benefits, risks, fertility and the monitoring schedule, then the Treatment and Monitoring guides below for the evidence on each product and what gets checked. If a product is reported short, the shortages page explains what to ask.
Then: the Regulation guides for what the rules allow in Canada and elsewhere.
The TRAVERSE trial testosterone results, the FDA label changes that followed in 2025 and 2026, and why Canadian labelling has not changed since July 2014.
How low testosterone is diagnosed in Canada: what symptoms, morning fasting blood testing and a search for the cause contribute, the threshold each body uses, and who should not start.
Oral testosterone undecanoate evidence: response rates, the blood pressure signal, hematocrit, the old liver case reports, and what Canada has marketed.
Testosterone and blood sugar: what the T4DM trial and meta-analyses report on glucose, HbA1c and body composition in men with confirmed low testosterone.
Testosterone gel evidence on absorption, DHT and skin transfer to partners and children, which gels Canada has, and why cream has never been sold here.
Compounded testosterone has no DIN and no Notice of Compliance. How Canada, the US, the UK and Australia regulate it, and the little evidence published.
The 13 testosterone products marketed in Canada on 14 September 2026, with DIN, form and company, plus the brands cancelled in 2025 and what Canada lacks.