What people say about testosterone therapy, and what we think
The guidelines agree on the core: treat men who have symptoms and a low level confirmed by
repeat morning blood tests, and not men whose level is normal. Beyond that, opinion splits.
Some well-known doctors and podcasters push testosterone further than the trials go, and
many of them sell testing, supplements or clinic services. Serious news coverage is
sceptical of the boom, not of treatment for confirmed deficiency. This page sets out each
side with dates, credentials and financial interests, then gives this site’s own view.
How to read this page
Three questions are worth asking of anyone who talks about testosterone, including this site:
What is their actual training? A urologist or endocrinologist, a family physician, a scientist who is not a clinician, and a content creator are different kinds of source.
Do they earn money from testosterone? From a clinic, a lab testing company, a supplement brand, a drug maker or a paid course. A financial interest does not make someone wrong, but it should travel with what they say.
Does what they say match the trials? Most of the evidence comes from men with confirmed low testosterone. Claims about men with normal levels, or about longer life, sit outside it.
Nobody named on this page endorses this site or any provider, and nobody was asked to. The
descriptions are paraphrased from the dated source linked beside each one, with short quotations
only where the wording matters.
What the guidelines say
Guidelines are written by committees that weigh the whole body of evidence, which makes them
slower than podcasts and more cautious. These are the documents that matter most in Canada, with
their dates.
Guidelines and regulators on who should be treated, most Canadian first.
Body and document
Date
What it says
Worth knowing
Health Canada, Information Update
15 July 2014
Testosterone should not be used for non-specific symptoms unless laboratory tests have confirmed a low level and other possible causes have been excluded.
Health Canada has issued nothing further on testosterone since.
Canadian product monograph, oral testosterone undecanoate
Authorized 12 December 2025
Deficiency must be shown by clinical features and confirmed by two separate validated morning blood tests. Safety and efficacy for age-related hypogonadism are not established.
No numeric threshold is printed.
Canadian Urological Association guideline (Grober and colleagues)
2021
The evidence-based questions and answers Canadian urologists work from.
Its authors include Mohit Khera and Abraham Morgentaler, whose financial interests are listed below.
Canadian Pharmacists Journal practice guideline (Beahm and colleagues)
October 2021
A low testosterone level on its own, without supporting signs and symptoms, is not a reason to treat.
The paper states it was not funded and its authors declare no conflicts. It was written before TRAVERSE.
Endocrine Society guideline (Bhasin and colleagues)
2018
Symptoms plus consistently low morning fasting total testosterone, confirmed on repeat testing, with an evaluation of the cause.
No single cut-off in the text used here.
European Association of Urology guideline
2026 edition, updated March 2026
A strong recommendation for a threshold of 12 nmol/L, measured fasting between 07:00 and 10:00 and confirmed on two occasions.
The clearest threshold among the documents listed here.
United States Food and Drug Administration, class labelling change
28 February 2025
Removed the boxed warning language on cardiovascular risk and added the TRAVERSE results to all testosterone labels.
Canada has not made an equivalent change.
Where they agree
Symptoms alone are not a diagnosis. A low level has to be confirmed with repeat morning blood tests.
Men whose testosterone is normal should not be treated.
The cause should be looked for, and reversible causes such as weight, sleep apnea and some medications come first.
Treatment needs monitoring, above all hematocrit, and it suppresses fertility.
Where they differ
The number. The European guideline gives 12 nmol/L. Canadian labels print no number and leave it to the laboratory range and the clinician. The detail is in the guide on how low testosterone is diagnosed in Canada.
Older men. The Canadian monograph says safety and efficacy for age-related decline are not established. The US regulator relaxed its cardiovascular warning in 2025 after TRAVERSE. Canada has not changed its labelling.
Independence. The pharmacist guideline declares no funding and no conflicts. The urology guideline includes authors with consulting ties to testosterone makers.
What it costs, beyond the headline fee
The fee that shows up first in an ad or a search result is rarely the whole bill. A low consult
or membership fee may not include the medication, and some services add a subscription, programme
or renewal fee every month or every few months. What matters is the total for a year: medication,
every recurring fee, and whatever a service does not publish.
The table puts the services that publish enough to estimate a year side by side, lowest estimate
first.
Editorial estimates by this site for an ongoing year, ordered by the lower end of each range. Actual costs depend on treatment and coverage; optional supplies are left out for every provider. Calculated on 28 September 2026 from published prices.
Medication, plus the $11.99 dispensing fee per prescription, three fills a year. No membership fee is stated. Assessment, requisitions, consultations, follow-ups and standard shipping: $0, as published.
Injection supplies (no price stated). Any uninsured lab charges.*
Twelve $170 subscription payments, medication and the published blood testing allowance. The published prices conflict and need clarification.†
Optional supplies: $50 a year if needed. Unconfirmed dispensing and shipping charges.
* For UPGUYS and Essential Clinic, the provider states that lab tests are generally covered by provincial plans. In some cases, the lab may charge for certain uninsured tests.
† The upper estimate for Enhanced Men’s Clinic leaves out the optional $50 supply charge. Its conflicting subscription and bundle prices, and the lab allowance that applies to an ongoing year, still need confirmation.
Too little published to estimate a year: Gambit, Gameday Men's Health, MHC, Phoenix, Sovereign Male. The arithmetic, assumptions and published prices behind each figure are on the cost page and in estimates.csv.
Two things the table cannot show. Products and doses differ, so the figures are not like for like.
And each figure is a subtotal: lab tests, supplies and anything else a service does not publish are
left out and named in the last column. Ask any service for its full yearly cost in writing before
you start.
What doctors, researchers and podcasters say
The people below were chosen because they shape what Canadians hear about testosterone, not
because the site agrees with them. Each entry keeps the credential, a dated source, what they
say and their financial interests together. Links were rechecked on
24 September 2026.
Researchers and clinicians
Peter J. Snyder, MD
Endocrinologist, Perelman School of Medicine, University of Pennsylvania. Led the Testosterone Trials and the fracture substudy of the TRAVERSE trial.
What they say
Lists better libido and sexual function, a small gain in energy, and higher red blood count, bone density and strength, and adds that "these benefits apply only to men who have low testosterone, unequivocally." Source: NPR, 10 August 2026
Financial interests
None stated in the report. The TRAVERSE trial he worked on was funded by AbbVie, a testosterone maker.
Steven Woloshin, MD
Professor of medicine, The Dartmouth Institute for Health Policy and Clinical Practice.
What they say
The most critical voice in recent coverage. On widening access to testosterone: "I think it is too soon." He disputes claims that it lengthens life. Source: NPR, 10 August 2026
Financial interests
No financial tie to a testosterone maker found.
Jamin Brahmbhatt, MD
Urologist, Orlando Health.
What they say
Supports treatment for men who need it and criticizes clinics that prescribe without proper testing and follow-up: "Not every guy needs to be on it." Source: NPR, 21 July 2026
Financial interests
None stated in the report.
Mohit Khera, MD
Professor of urology, Baylor College of Medicine. Co-author of the TRAVERSE trial and of the 2021 Canadian Urological Association guideline.
What they say
Among the most guideline-faithful of the well-known names. He says a man with a normal level should not be treated even when he has symptoms, and warns that a rise in hematocrit is most common with injections and that testosterone therapy can cause infertility. Source: BackTable Urology, episode 124, 4 October 2023
Financial interests
The American Urological Association’s 2024 disclosure list shows current consulting or advisory roles with Coloplast, Endo, Halozyme, Marius Pharmaceuticals and Tolmar, and stock options in Sprout Pharmaceuticals and Vault Health, a men’s health telehealth company. Marius and Tolmar sell oral testosterone products. Source: AUA 2024 Annual Meeting, instructional course faculty disclosures, 2024 annual meeting
Abraham Morgentaler, MD
Urologist, Harvard Medical School. Founder of Men’s Health Boston and co-author of the 2021 Canadian Urological Association guideline.
What they say
The most quoted clinician in favour of testosterone therapy. His central argument is that treatment does not raise prostate cancer risk in men with low testosterone. In a 2026 lecture he acknowledged that prospective trials are still needed. Source: STAT, "The doctor who overturned medicine’s fear of testosterone", 23 December 2025
Financial interests
Founded Men’s Health Boston, a clinic that provides testosterone therapy. The American Urological Association’s 2023 disclosure list shows past consulting for Acerus and Marius Pharmaceuticals and lecturing for Besins Healthcare, all testosterone makers, with end dates in 2021 and 2022. Source: AUA 2023 society meeting disclosures, 2023 annual meeting
Canadian voices
Larry Goldenberg, MD, and Ryan Flannigan, MD
Urologists, Department of Urologic Sciences, University of British Columbia. Goldenberg founded the Canadian Men’s Health Foundation and the Vancouver Prostate Centre.
What they say
The foundation page they reviewed is careful and conditional. It says therapy is usually lifelong, is likely to stop sperm production, can cause acne, oily skin and hair loss, and thickens the blood when levels go too high. Source: Canadian Men’s Health Foundation, "Low Testosterone In Men", 15 September 2023
Financial interests
The foundation is a non-profit. No tie to a testosterone maker found. Flannigan also practises at a private fertility clinic.
Canadian mainstream coverage is listed under what the news coverage says.
Very few Canadian clinicians speak about testosterone publicly outside professional settings.
Podcasters and content creators
Peter Attia, MD
Physician and host of The Drive podcast. Not board certified in endocrinology or urology.
What they say
His review of TRAVERSE lists benefits in men with low testosterone: body composition, muscle and strength, bone density, sexual desire and function, mood and quality of life. He is more conservative than most in this group and describes treating only when there are symptoms. Source: peterattiamd.com, review of the TRAVERSE trial, 25 October 2023
Financial interests
Founder of Early Medical, a paid medical practice. Source: peterattiamd.com, About, no date shown
Against the evidence
The benefits he lists come from trials in men with confirmed low testosterone. Thresholds looser than the guidelines widen who would be treated beyond the men those trials studied.
Andrew Huberman, PhD
Professor of neurobiology, Stanford School of Medicine. Not a physician.
What they say
Draws a useful line between treating men below the reference range and raising levels in men already within it. In this January 2026 episode he said he is on low-dose TRT, started at 45, and that others should wait if they do it at all. Source: Huberman Lab, episode with Dorian Yates, 19 January 2026
Financial interests
Paid scientific advisor to AG1, Eight Sleep, Function Health, Momentous, Reveri and WHOOP, as his own disclaimer page states. Momentous sells a hormone support supplement bundle. Source: Huberman Lab, disclaimer page, no date shown
Against the evidence
Supplements discussed on the show for raising testosterone, such as fadogia agrestis, have essentially no human safety or efficacy data.
Rena Malik, MD
Board-certified urologist with a large YouTube and podcast audience.
What they say
Her January 2026 solo episode is critical of the TRT market, with chapters on expert bias, abuse versus therapeutic use, online prescribing and adulterated supplements. Source: Rena Malik podcast, solo episode on testosterone, 23 January 2026
Financial interests
Listed as having no relevant financial relationships in the American Urological Association’s 2023 disclosure list. She sells her own courses, a membership and a book. Source: AUA 2023 society meeting disclosures, 2023 annual meeting
Against the evidence
Guests on her channel sometimes make stronger claims than she does. Those claims are the guest’s, not hers.
Barbell Medicine (Jordan Feigenbaum, MD, and Austin Baraki, MD)
Two physicians who run a coaching and education business.
What they say
A single low result is not a diagnosis, many first low results are normal on repeat testing, and reversible causes such as untreated sleep apnea and excess abdominal fat come first. They accept the benefits in properly diagnosed men and say plainly that raising testosterone within the normal range will not deliver what marketing promises. Source: Barbell Medicine, "Low Testosterone in Men", 5 June 2026
Financial interests
They sell a testosterone course and book. Their commercial interest points away from prescribing, not toward it.
Layne Norton, PhD
PhD in nutritional sciences and a coach. Not a physician.
What they say
A critic of testosterone marketing. Says differences within the normal range do not predict muscle gain and that testosterone boosting supplements do not work. He does not dispute that diagnosed hypogonadism can be treated. Source: Men’s Health, "Why Is Everyone Suddenly Taking Testosterone?", 26 August 2026
Financial interests
Owns a supplement company that sells no hormone products.
Gabrielle Lyon, DO
Board-certified family physician. Not a urologist or endocrinologist.
What they say
Presents testosterone within her "muscle-centric medicine" framing. Chapters of her episodes include "Low Testosterone is a Predictor of Heart Disease" and ask whether TRT protects the heart. Source: The Dr. Gabrielle Lyon Show, "TRT Risks & Rewards", 21 October 2025
Financial interests
Founded Strong Medical, a paid concierge practice whose services include hormone optimization. Source: Strong Medical, no date shown
Against the evidence
TRAVERSE was a safety trial and showed no cardiovascular benefit. Its fracture substudy found more fractures on testosterone, not fewer.
Chief medical officer of Function Health, a direct-to-consumer lab testing membership that includes hormone panels. Source: Function Health, About, no date shown
Against the evidence
The population decline is contested, and it does not show that any one man needs treatment. A lab testing business gains when more men test their hormones.
Rhonda Patrick, PhD
PhD in biomedical science. Not a physician.
What they say
Her testosterone content is almost entirely interviews, so claims on her channel belong to the guest. Her own summary of this September 2025 episode calls testosterone a cornerstone of health that influences mood, cognition, bone density, libido and even longevity. Source: FoundMyFitness, episode 106 with Derek of More Plates More Dates, 9 September 2025
Financial interests
No tie to testosterone or hormone products found.
Against the evidence
Longer life is not an outcome any testosterone trial has shown. The guest in that episode holds no medical credential and co-founded Marek Health, a lab testing company.
Named because they drive the conversation, not cited as sources
Joe Rogan has said on air that he takes testosterone replacement, as quoted by WBUR’s On Point
on 19 February 2025. He has no health credential. Derek, the host of
More Plates More Dates, has no medical credential and co-founded Marek Health, a lab testing
company, and a supplement brand. Both reach very large audiences and both are part of why men
ask about testosterone. Neither is a source for a clinical claim on this site.
Where the public conversation goes beyond the evidence
These claims come up often. Here is what the trials show.
TRAVERSE, in 5,246 men with confirmed low testosterone and heart risk, found major cardiac events in 7 percent on testosterone and 7.3 percent on placebo, per the current US label. That is a safety result, not a benefit. Atrial fibrillation, pulmonary embolism and acute kidney injury were more common on testosterone. See the TRAVERSE trial.
It builds bone, so it prevents fractures.
Bone density rises on treatment, but the TRAVERSE fracture substudy found clinical fractures in 3.50 percent of men on testosterone and 2.46 percent on placebo. See the TRAVERSE trial.
Raising a normal level improves energy, muscle and sex drive.
The trials enrolled men with confirmed low levels. A pooled analysis of 17 trials (Isidori 2005) found no effect on sexual function in men whose testosterone was already normal. See how low testosterone is diagnosed.
Supplements can raise your testosterone.
Experts interviewed by CBC’s White Coat, Black Art on 28 September 2025 said testosterone supplements will not boost hormone levels. Herbal products promoted online, such as fadogia agrestis, have essentially no human safety or efficacy data.
Men’s testosterone is falling, so most men need it.
Population trends are contested, and they say nothing about whether one man needs treatment. Diagnosis rests on that man’s symptoms and repeat blood tests.
What patients say
This site does not publish individual patient testimonials. One person’s account cannot show
what a treatment does, and testimonials about a prescription drug are a form of promotion. What
follows comes from studies that looked at many patients at once.
What men talk about online. Urologists at UCLA analysed 199,335 posts in
Reddit’s r/Testosterone forum from December 2015 to May 2019, and 6,659 tweets (Osadchiy,
Journal of Medical Internet Research, 7 October 2020). The main
themes were symptoms, seeing a doctor, lab results, the medications, heart risk, and insults.
More than a quarter of the Reddit posts mentioned a doctor. The authors describe men who feel
discouraged by their doctors turning to social media instead.
How long men stay on treatment, in Ontario. A study of 4,797 Ontario men aged
66 and over who started testosterone between 2009 and 2012 found that only 38.7 percent met the
public plan’s criteria before starting. Median time to stopping was 383 days for oral capsules,
319 days for gels, 283 days for injections and 160 days for patches. Many stopped within a year
(Martins, Pharmacoepidemiology and Drug Safety, 2016).
Why men stop. In a Korean study of 640 men over 40 followed for more than ten
years, 75.9 percent were still on treatment after one year. The reasons for stopping, most common
first, were inconvenience, cost, worry about side effects, not feeling a benefit, and symptoms
improving (Kang, World Journal of Men’s Health, 2021).
What matters to men using it. Interviews with 58 American men on testosterone
found eight things that shaped their view of treatment: ease of use, effect on libido, the
product itself, physical effects, psychological effects, side effects, the overall treatment
experience, and preference. Most of them preferred a gel to an injection or a patch (Szeinbach,
Patient Preference and Adherence, 2012).
Public reviews of Canadian services. The review scores on the
providers page are platform displays with dates. They reflect the
service experience reviewers chose to write about, not whether treatment worked for them
medically, and some companies invite their customers to review.
Across these studies, a pattern shows. Many men look for answers online when they feel unheard, a
large share stop within the first year, and cost, inconvenience and side effects are the usual
reasons. That is worth knowing before starting a treatment that is usually meant to be long term.
What the news coverage says
The weight of serious coverage since TRAVERSE is sceptical of the testosterone boom, of treating
men with normal levels and of online clinics that skip testing. It is not sceptical of treating
confirmed deficiency. Newest first:
One caution. Some newspaper websites, including The Globe and Mail’s markets pages, republish
paid press releases from testosterone clinics under their own web address. Those are
advertising, not journalism, and they are not listed here.
Our view
This section is the site’s own opinion. It is kept apart from the facts above so it can be read,
and disagreed with, as opinion.
For men with confirmed low testosterone and symptoms, treatment is established
medicine. The trials show real gains in sexual function, bone density and red blood
count, and reassurance on major heart events. They also show costs: a rise in hematocrit that has
to be watched, more atrial fibrillation, pulmonary embolism and fractures in TRAVERSE, and
suppressed fertility.
The public conversation has run ahead of the evidence. Longer life, heart
protection, and more energy or muscle for men whose levels are already normal are not trial
results. Several of the loudest voices sell testing, supplements or clinic services. That does
not make them wrong, but it is worth knowing before taking their advice.
How care is delivered matters more than whether it is online or in person.
These are the questions we would ask of any service, including every provider on this site:
Does it confirm a low result with repeat morning blood tests before treating?
Does it look for a cause, such as sleep apnea, weight, medications or a pituitary problem?
Does it talk about fertility before starting, if children are still a possibility?
Does it check hematocrit and other blood work on a schedule, and act on the results?
Does it name the licensed pharmacy that dispenses the prescription?
Does it tell you the total for a year, medication and every recurring fee included, before you sign up, and not only the headline fee?
Is it easy to stop, and does it explain what stopping involves?
What each provider publishes on these points is in the providers table.
If your level is normal, testosterone is not the answer to how you feel. A
service that treats a normal level is working outside every guideline on this page.
If your level is low, the next conversation is about why, and about fertility,
before it is about which product.
Common questions
Should I take testosterone if my level is normal?
No guideline supports it. Every guideline on this page limits treatment to men with symptoms and a low level confirmed by repeat morning blood tests, and a pooled analysis of 17 trials found no sexual function benefit in men whose testosterone was already normal.
Is testosterone therapy safe for the heart?
In TRAVERSE, 5,246 men with confirmed low testosterone and heart risk had major cardiac events at about the same rate on testosterone as on placebo. That is a safety result, not a benefit. Atrial fibrillation, pulmonary embolism and fractures were more common on testosterone, and hematocrit has to be monitored.
What does testosterone therapy cost per year in Canada?
It depends on the service and on what it charges beyond the headline fee. For the services that publish enough to estimate a year, this site's estimated yearly subtotals, lowest first, are: UPGUYS $636 to $1,236; Jack Health $872 to $1,880; Essential Clinic $1,312 to $1,460; Science & Humans $1,520 to $1,880; Enhanced Men's Clinic $2,300 to $2,860. Lab tests and any fees a service does not publish are extra. Gambit, Gameday Men's Health, MHC, Phoenix and Sovereign Male publish too little to estimate. Figures calculated 28 September 2026.
Do the doctors and podcasters on this page endorse this site?
No. Nobody named on this page endorses this site or any provider, and nobody was asked to. Each is described from their own dated public statements and disclosures.